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Abstract visualization of probiotics and prebiotics in the gut microbiome
Food, Personal & Home Care

Gut-Health Functional Foods

Scouting, testing, and ranking next-generation probiotic-prebiotic combinations that survive manufacturing, earn credible health claims, and appeal to a broad consumer base.

Client

Multinational Food & Beverage Co.

Objective

Identify & Prioritise Synbiotic Pairs

Timeline

10-Week Program

Key Focus

Strain Survivability & Claims

The Challenge: From Lab Insights to Everyday Foods

While the science of synbiotics (probiotics + prebiotics) is promising, translating it into successful consumer products is difficult. Beneficial strains often die during processing or storage, health effects are highly strain-specific, and one-size-fits-all products can be unreliable due to microbiome variability. On top of this, regulatory agencies demand robust human data to substantiate any health claims.

Survivability: Probiotic strains must remain viable (≥10⁸ CFU/serving) through processing stress and a six-month shelf life.
Credible Claims: Each strain-fiber pair needs human-study evidence for benefits like digestive comfort to meet regulator demands.

A 5-Phase, 10-Week Execution Strategy

1

Weeks 1-2: Landscape Scan

Searched 2,500 papers and 1,300 patents to shortlist 50 probiotic strains and 20 prebiotic fibers.

2

Weeks 3-4: Bench Screening

Ran heat-shock and acid-tolerance tests; co-cultured strains with fibers to measure growth boost.

3

Weeks 5-6: Pilot Formulation

Encapsulated top 12 pairs and processed them through pilot trials to measure CFU retention.

4

Weeks 7-8: Evidence & Claims Mapping

Matched each pair to published human data and drafted acceptable claim language for US and EU markets.

5

Weeks 9-10: Prioritisation & Roadmap Delivered top-5 ranked ingredient systems with cost models and a 12-month path to market.

Key Outcomes: A Ready-to-Launch Product Pipeline

Our program delivered a shortlist of high-priority synbiotic systems with clear performance data, cost models, and a regulatory roadmap.

5 High-Priority Systems

Each system identified retained >80% viability after six months at ambient humidity.

Claim-Ready Pair

One *Lactobacillus plantarum* + resistant-starch pair showed a 3-log CFU growth boost and met evidence thresholds for a "Helps maintain regularity" claim.

Competitive Costing

Encapsulation cost was modeled at <$0.02 per serving, competitive with current premium yogurt formulations.

Strategic Impact

The client approved pilot production of the top two synbiotic blends for a granola bar and a smoothie. With a clear evidence dossier and claim language in hand, the company is positioned to launch a science-verified gut-health product line in three regions within the next 18 months.